During a class trip to Aruba, a carefree night out with friends turns tragic for Natalee Holloway. When the Alabama teenager disappears without a trace, her island vacation becomes a harrowing nightmare for her family. With no clue as to her whereabouts, her mother, Beth Holloway Twitty (Tracy Pollan), is launched into a frustrating search that spans more than four years. Along with her husband George (Grant Show) and her best friend Carol (Catherine Dent), Beth struggles to uncover the truth. Based upon the book Loving Natalee by Beth Holloway Twitty.

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